Clinical recommendation	Evidence rating	References
Postinflammatory hyperpigmentation may be improved with hydroquinone (Eldoquin Forte), azelaic acid (Azelex), retinoids, glycolic acid peels, and laser therapy; monotherapy is often unsatisfactory.	C	4–6
Treatment of epidermal melasma with triple therapy is more effective than treatment with hydroquinone, fluocinonide (Lidex, brand no longer available in the United States), or tretinoin (Retin-A) alone or in double combination.	B	16, 17
Chemical peels and brief cryotherapy are effective ablative treatments for solar lentigines.	C	20–22
For the treatment of localized and generalized vitiligo, high-potency steroids, topical or oral psoralens with psoralen ultraviolet A-range, and narrow-band ultraviolet-B therapies are beneficial. Vitiligo of the head and neck is most responsive to treatment.	B	32, 36–44