Indication	Medication	Typical dosage	Route	Fracture type	Monthly cost*
Prevention	Estrogen†, with or without progesterone	0.625 mg daily	Oral	Hip, vertebral, nonvertebral	With progesterone: $40 Without progesterone: $47
Prevention and treatment	Alendronate (Fosamax)	70 mg weekly	Oral	Hip, vertebral, nonvertebral	Tablet: $87, $77 (generic) Solution: $96
	Ibandronate (Boniva)	150 mg monthly	Oral	Vertebral	$100
	Risedronate (Actonel)	35 mg weekly	Oral	Hip, vertebral, nonvertebral	$92
	Raloxifene (Evista)	60 mg daily	Oral	Vertebral	$108
Treatment	Ibandronate	3 mg every three months for four doses	Intravenous	Increases bone mineral density, but fracture end point not evaluated	$162‡
	Zoledronic acid (Reclast)	5 mg annually for three doses	Intravenous	Hip, vertebral, nonvertebral	$104
	Calcitonin (Miacalcin)	200 IU daily	Nasal	Vertebral	$126
	Teriparatide (Forteo)	20 mcg daily up to two years	Subcutaneous	Vertebral, nonvertebral	$675