AgentDoseRisksContraindications
Activated charcoal*†1 to 2 g per kg (maximum of 50 to 60 g)Aspiration, constipation, vomitingUnlikely to benefit patients who ingested alcohols, strong acids or bases, minerals, iron, lithium, or hydrocarbon
Gastric lavage*†10 to 15 mL per kg saline instilled via large-bore orogastric tube, repeated until aspirates clearEsophageal/laryngeal trauma, aspiration, nausea/vomiting, impaired level of consciousnessUnprotected airway, ingestion of hydrocarbons or corrosives, risk of perforation or hemorrhage
Polyethylene glycol (used with whole bowel irrigation)500 mL per hour for children nine months to five years of age
1,000 mL per hour for children six to 12 years of age
Vomiting, crampingUnprotected airway, intractable vomiting, gastrointestinal hemorrhage, ileus, perforation, obstruction
Sorbitol (used with activated charcoal)1 to 2 g per kgHypernatremia, dehydrationObstruction, perforation, ileus