Clinical recommendation	Evidence rating	References
The muscarinic agonists pilocarpine (Salagen) and cevimeline (Evoxac) can be used to relieve xerophthalmia in patients with Sjögren syndrome.	B	21, 22
Muscarinic agonists improve subjective and objective signs and symptoms of xerostomia in patients with Sjögren syndrome.	B	25, 26
Interferon alfa improves subjective oral and ocular dryness and increases nonstimulated saliva flow in patients with Sjögren syndrome.	B	7