Ashkenazi Jewish women*

One first-degree relative with breast or ovarian cancer

Two second-degree relatives on the same side of the family with breast or ovarian cancer

All other women

Two first-degree relatives with breast cancer, one of whom was diagnosed by 50 years of age

Three or more first- or second-degree relatives with breast cancer

A combination of breast and ovarian cancers among first- and second-degree relatives

One first-degree relative with bilateral breast cancer

Two or more first- or second-degree relatives with ovarian cancer

One first- or second-degree relative with the combination of breast and ovarian cancer

Breast cancer in a male relative