Agent (brand name)	Manufacturer	Active component	Duration of action
Cosmoplast	Allergan Inc.	Collagen	3 to 4 months
Restylane	Medicis Aesthetics	Hyaluronic acid	6 to 9 months
Perlane	Medicis Aesthetics	Hyaluronic acid	6 to 9 months
Juvéderm	Allergan Inc.	Hyaluronic acid	9 to 12 months
Radiesse	Bioform Medical Inc.	Calcium hydroxylapatite	12 to 18 months
Sculptra	Dermik Laboratories	Poly-l-lactic acid	12 to 24 months