Patient population	Criteria
Patients with more than a 20 to 25 percent chance of having an inherited predisposition to breast and ovarian cancers, and for whom genetic risk assessment is recommended	Women with a personal history of breast and ovarian cancers*
	Women with ovarian cancer* and a close relative† with ovarian cancer, premenopausal breast cancer, or both
	Women with ovarian cancer* who are of Ashkenazi Jewish ancestry
	Women 50 years and younger with breast cancer and a close relative† with ovarian cancer* or male breast cancer at any age
	Women of Ashkenazi Jewish ancestry in whom breast cancer was diagnosed at 40 years or younger
	Women with a close relative† with a known BRCA1 or BRCA2 mutation
Patients with more than a 5 to 10 percent chance of having an inherited predisposition to breast and ovarian cancers, and for whom genetic risk assessment may be helpful	Women with breast cancer at 40 years or younger
	Women at any age with ovarian cancer, primary peritoneal cancer, or fallopian tube cancer of high grade, serous histology
	Women with bilateral breast cancer (particularly if the first case of breast cancer was diagnosed at 50 years or younger)
	Women with breast cancer at 50 years or younger and a close relative † with breast cancer at 50 years or younger
	Women of Ashkenazi Jewish ancestry with breast cancer at 50 years or younger
	Women with breast cancer at any age, and two or more close relatives † with breast cancer at any age (particularly if at least one case of breast cancer was diagnosed at 50 years or younger) Unaffected women with a close relative† that meets one of the previous criteria