| What are the effects of nonsurgical treatments for women with stress incontinence? |
| Likely to be beneficial | Pelvic floor electrical stimulation |
| Pelvic floor muscle exercises |
| Selective serotonin reuptake inhibitors (duloxetine) |
| Vaginal cones |
| Trade-off between benefits and harms | Estrogen supplements |
| Unknown effectiveness | Adrenoceptor agonists |
| What are the effects of surgical treatments for women with stress incontinence? |
| Beneficial | Laparoscopic colposuspension (similar cure rates to open retropubic colposuspension and TVT) |
| Open retropubic colposuspension (higher cure rates than nonsurgical treatment, anterior vaginal repair, or needle suspension, and similar cure rates to laparoscopic colposuspension, traditional suburethral slings, transobturator foramen procedures, and TVT) |
| Suburethral slings other than TVT (similar cure rates to open retropubic colposuspension, TVT, and needle suspension, but more perioperative complications than needle suspension) |
| Likely to be beneficial | Transobturator foramen procedures (similar cure rates to TVT and open retropubic colposuspension) |
| Trade-off between benefits and harms | TVT (similar cure rates to laparoscopic colposuspension, non-TVT suburethral slings, transobturator foramen procedures, and open retropubic colposuspension, but associated with more bladder and vaginal perforations) |
| Unlikely to be beneficial | Anterior vaginal repair (lower cure rates than open retropubic colposuspension, but similar cure rates to needle suspension) |
| Needle suspension (lower cure rates and more surgical complications than open retropubic colposuspension) |