OrganizationRecommendations
Diabetes
AACE32 All persons 30 years or older who are at risk of having or developing type 2 diabetes should be screened annually.
ADA8 *Testing to detect type 2 diabetes should be considered in asymptomatic adults with a BMI of 25 kg per m2 or greater and one or more additional risk factors for diabetes.
Additional risk factors include physical inactivity; hypertension; HDL cholesterol level of less than 35 mg per dL (0.91 mmol per L) or a triglyceride level of greater than 250 mg per dL (2.82 mmol per L); history of CV disease; A1C level of 5.7 percent or greater; IGT or IFG on previous testing; first-degree relative with diabetes; member of a high-risk ethnic group; in women, history of gestational diabetes or delivery of a baby greater than 4.05 kg (9 lb), or history of PCOS; other conditions associated with insulin resistance (e.g., severe obesity, acanthosis nigricans).
In persons without risk factors, testing should begin at 45 years of age.
If test results are normal, repeat testing should be performed at least every three years.
CTFPHC33 There is fair evidence to recommend screening patients with hypertension or hyperlipidemia for type 2 diabetes to reduce the incidence of CV events and CV mortality.
USPSTF34 All adults with a sustained blood pressure of greater than 135/80 mm Hg should be screened for diabetes.
Current evidence is insufficient to assess balance of benefits and harms of routine screening for type 2 diabetes in asymptomatic, normotensive patients.
Gestational diabetes
AACE32 In all pregnant women, fasting glucose should be measured at the first prenatal visit (no later than 20 weeks' gestation).
A 75-g OGTT should be performed if the fasting glucose concentration is greater than 85 mg per dL (4.7 mmol per L).
ACOG35,36 *All pregnant women should be screened through history, clinical risk factors, or laboratory testing.
Women at low-risk may be excluded from glucose testing.
Low-risk criteria include age younger than 25 years, BMI of 25 kg per m2 or less, no history of abnormal OGTT result, no history of adverse obstetric outcomes usually associated with gestational diabetes, no first-degree relative with diabetes, not a member of a high-risk ethnic group.
Women with gestational diabetes should be screened six to 12 weeks postpartum and should receive subsequent screening for the development of diabetes.
ADA1,8 *Risk assessment should be performed at the first prenatal visit.
Women with clinical characteristics consistent with a high risk of gestational diabetes (e.g., marked obesity, personal history of gestational diabetes, glycosuria, strong family history of diabetes) should undergo glucose testing as soon as possible. If glucose test results are negative, retesting should be performed at 24 to 28 weeks' gestation.
Testing may be excluded in low-risk women (see ACOG criteria above). All other women should receive Glucola test or OGTT at 24 to 28 weeks' gestation.
Women with gestational diabetes should be screened for diabetes six to 12 weeks postpartum and should receive subsequent screening for the development of diabetes.
CTFPHC37 There is poor evidence to recommend for or against screening using Glucola testing in the periodic health examination of pregnant women.
USPSTF38 Evidence is insufficient to assess the balance of benefits and harms of screening for gestational diabetes, either before or after 24 weeks' gestation.
Physicians should discuss screening with patients and make case-by-case decisions.