Drug	Adult dosage*	Undetectable HBV DNA at one year (%)	Histologic improvement in one year (%)	Durability of response at one year (%)†
Injectable
Pegylated interferon alfa-2a (Pegasys)	180 mcg per week	63	48	18
Oral
Adefovir (Hepsera)	10 mg per day	51 to 64	64	< 10
Entecavir (Baraclude)	0.5 mg per day	90	70	NA
Lamivudine (Epivir)	100 mg per day	60 to 73	61 to 66	< 10
Telbivudine (Tyzeka)	600 mg per day	88	67	NA
Tenofovir (Viread)	300 mg per day	95	72	NA