Clinical recommendations	Evidence rating	References
HIV infection should be confirmed with repeat HIV enzyme-linked immunoabsorbent assay and Western blot test to document seroconversion within four to six weeks.	C	19, 20
Patients with acute HIV infection should receive education and counseling on strategies to reduce the risk of transmission.	C	23, 24
Following diagnosis of acute HIV infection, two sets of CD4 lymphocyte counts and HIV viral load levels should be checked within four to six weeks to monitor level of immune suppression and viremia.	C	27
Patients with acute HIV infection should be screened for sexually transmitted infections (e.g., chlamydia, gonorrhea, syphilis), hepatitis B and C, and tuberculosis.	C	27
An HIV genotype should be strongly considered to assess for baseline resistance mutations.	C	27, 29
Consultation with an HIV specialist should occur before initiation of antiretroviral therapy.	C	30, 31