| Intranasal corticosteroids |
| Beclomethasone (Beconase) | C | Six years | Inhibits the influx of inflammatory cells; onset of action is less than 30 minutes | Bitter aftertaste, burning, epistaxis, headache, nasal dryness, potential risk of systemic absorption, rhinitis medicamentosa, stinging, throat irritation |
| Budesonide (Rhinocort) | B | Six years |
| Ciclesonide (Omnaris) | C | Six years |
| Flunisolide | C | Six years |
| Fluticasone furoate (Veramyst) | C | Two years |
| Fluticasone propionate (Flonase) | C | 12 years |
| Mometasone (Nasonex) | C | Two years |
| Triamcinolone (Nasacort) | C | 12 years |
| Oral antihistamines |
| Cetirizine (Zyrtec) | B | Six months | Blocks H1 receptors; onset of action is 15 to 30 minutes | Dry mouth, sedation at higher than recommended doses |
| Desloratadine (Clarinex) | C | Six months |
| Fexofenadine (Allegra) | C | Six months |
| Levocetirizine (Xyzal) | B | 12 years |
| Loratadine (Claritin) | B | Two years |
| Intranasal antihistamines |
| Azelastine (Astelin) | C | Five years | Blocks H1 receptors; onset of action is 15 minutes | Bitter aftertaste, epistaxis, headache, nasal irritation, sedation |
| Olopatadine (Patanase) | C | Six years |
| Oral decongestants |
| Pseudoephedrine | C | 12 years | Vasoconstriction; onset of action is 15 to 30 minutes | Arrhythmias, dizziness, headache, hypertension, insomnia, nervousness, tremor, urinary retention |
| Intranasal cromolyn |
| Cromolyn (Nasalcrom) | B | Two years | Inhibits histamine release; results typically noted in one week, but may take two to four weeks for full effect | Epistaxis, nasal irritation, sneezing |
| Intranasal anticholinergics |
| Ipratropium (Atrovent) | B | Six years | Blocks acetylcholine receptors; onset of action is 15 minutes | Epistaxis, headache, nasal dryness |
| Leukotriene receptor antagonists |
| Montelukast (Singulair) | B | Six months | Blocks leukotriene receptors; onset of action is two hours | Elevated levels of alanine transaminase, aspartate transaminase, and bilirubin |