TreatmentPregnancy categoryMinimum ageMechanism and onset of actionAdverse effects
Intranasal corticosteroids
Beclomethasone (Beconase)CSix yearsInhibits the influx of inflammatory cells; onset of action is less than 30 minutesBitter aftertaste, burning, epistaxis, headache, nasal dryness, potential risk of systemic absorption, rhinitis medicamentosa, stinging, throat irritation
Budesonide (Rhinocort)BSix years
Ciclesonide (Omnaris)CSix years
FlunisolideCSix years
Fluticasone furoate (Veramyst)CTwo years
Fluticasone propionate (Flonase)C12 years
Mometasone (Nasonex)CTwo years
Triamcinolone (Nasacort)C12 years
Oral antihistamines
Cetirizine (Zyrtec)BSix monthsBlocks H1 receptors; onset of action is 15 to 30 minutesDry mouth, sedation at higher than recommended doses
Desloratadine (Clarinex)CSix months
Fexofenadine (Allegra)CSix months
Levocetirizine (Xyzal)B12 years
Loratadine (Claritin)BTwo years
Intranasal antihistamines
Azelastine (Astelin)CFive yearsBlocks H1 receptors; onset of action is 15 minutesBitter aftertaste, epistaxis, headache, nasal irritation, sedation
Olopatadine (Patanase)CSix years
Oral decongestants
PseudoephedrineC12 yearsVasoconstriction; onset of action is 15 to 30 minutesArrhythmias, dizziness, headache, hypertension, insomnia, nervousness, tremor, urinary retention
Intranasal cromolyn
Cromolyn (Nasalcrom)BTwo yearsInhibits histamine release; results typically noted in one week, but may take two to four weeks for full effectEpistaxis, nasal irritation, sneezing
Intranasal anticholinergics
Ipratropium (Atrovent)BSix yearsBlocks acetylcholine receptors; onset of action is 15 minutesEpistaxis, headache, nasal dryness
Leukotriene receptor antagonists
Montelukast (Singulair)BSix monthsBlocks leukotriene receptors; onset of action is two hoursElevated levels of alanine transaminase, aspartate transaminase, and bilirubin