Drug			Adult dosage*
Occupational exposures
Preferred basic two-drug regimens
	Zidovudine (Retrovir) plus lamivudine (Epivir); combination drug available as Combivir		Zidovudine: 300 mg twice daily with food
			Lamivudine: 150 mg twice daily
			Zidovudine/lamivudine: 300/150-mg tablet twice daily
	Zidovudine plus emtricitabine (Emtriva)		Zidovudine: 300 mg twice daily with food
			Emtricitabine: 200 mg once daily
	Tenofovir (Viread) plus lamivudine		Tenofovir: 300 mg once daily†
			Lamivudine: 150 mg twice daily
	Tenofovir plus emtricitabine; combination drug available as Truvada		Tenofovir: 300 mg once daily†
			Emtricitabine: 200 mg once daily
			Tenofovir/emtricitabine: 300/200-mg tablet once daily
Preferred expanded three-drug regimen
	Basic two-drug regimen plus lopinavir/ritonavir (Kaletra)		Lopinavir/ritonavir: two 200/50-mg tablets twice daily with food
Nonoccupational exposures‡
Preferred nonnucleoside reverse transcriptase inhibitor–based regimen
	Efavirenz (Sustiva)		Efavirenz: 600 mg once daily
	plus
	Lamivudine or emtricitabine		Lamivudine or emtricitabine; zidovudine or tenofovir: same dosing as above
	plus
	Zidovudine or tenofovir
	Efavirenz/emtricitabine/tenofovir combination available as Atripla		Efavirenz/emtricitabine/tenofovir: 600/200/300-mg tablet once daily
Preferred protease inhibitor–based regimen
	Lopinavir/ritonavir		Same dosing as above
	plus
	Lamivudine or emtricitabine
	plus
	Zidovudine