RegimenCommunity-acquired infection in childrenCommunity-acquired infection in adults
Mild to moderate infection*Severe infection or high-risk†
Single agentErtapenem (Invanz)CefoxitinDoripenem (Doribax)
Imipenem/cilastatin (Primaxin)ErtapenemImipenem/cilastatin
Meropenem (Merrem)Moxifloxacin (Avelox)Meropenem
Piperacillin/tazobactam (Zosyn)Ticarcillin/clavulanatePiperacillin/tazobactam
Ticarcillin/clavulanate (Timentin)Tigecycline (Tygacil)
Combination therapyOne of the following:

  • Cefepime (Maxipime)

  • Cefotaxime (Claforan)

  • Ceftazidime (Fortaz)

  • Ceftriaxone (Rocephin)

  • Plus metronidazole (Flagyl)

One of the following:

  • Cefazolin

  • Cefotaxime

  • Ceftriaxone

  • Ciprofloxacin (Cipro)

  • Levofloxacin (Levaquin)

Plus metronidazole‡		One of the following:

  • Cefepime

  • Ceftazidime

  • Ciprofloxacin

  • Levofloxacin

Plus metronidazole‡
or
One of the following:

  • Gentamicin

  • Tobramycin

  • Plus clindamycin (Cleocin) or metronidazole

  • With or without ampicillin