Clinical recommendation	Evidence rating	References	Comments
Elevated transaminase levels and nonalcoholic fatty liver disease are not contraindications to statin use.	C	1–4	Expert opinion,1 meta-analysis,2 small case-control studies3 ,4
Stable hepatitis C infection is not an absolute contraindication to statin use.	C	5–7	Small cohort study5 ; small prospective, double-blind, placebo-controlled study6 ; large cohort study7
Statin-induced myopathy is dose-related and may occur with all statins.	C	17	Systematic review of observational studies
Baseline levels of creatine kinase need to be obtained only in patients at high risk of muscle toxicity.	C	1, 16	Consensus guidelines