Increase weekly in increments of 2.5 to 5 mg, to maximum dosage of 20 mg per day

Doses should be spaced at least four hours apart

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Increase weekly in increments of 2.5 to 5 mg per dose

Take in morning and at noon; add 4 p.m. dose if needed

Typical dose is about one-half of equivalent methylphenidate dose

Increase each dose by 2.5 to 5 mg (depending on weight) every one to two weeks as needed and tolerated

Take in morning and at noon; add 4 p.m. dose if needed

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Increase in increments of 2.5 mg; dosage may be increased weekly up to 10 mg per day, to a maximum of 40 mg per day

Second dose can be added six to seven hours after morning dose; consider using a tapered dose (smaller afternoon dose than morning dose)

Length of action is typically five to eight hours, depending on dose; as dose increases, drug effects will last longer

Dosage may be increased weekly by 5 to 10 mg per day, to a maximum of 30 mg per day in children six to 12 years of age, or 20 mg per day in adolescents

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Increase weekly in increments of 5 mg, to a maximum dosage of 20 mg per day

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Add 5 mg of extended-release or immediate-release formulation to morning dose, to a maximum dosage of 40 mg per day

Typical dose is about one-half of equivalent methylphenidate dose

Increase weekly in increments of 10 to 20 mg per day, to a maximum dosage of 70 mg per day

Prodrug with a long duration of action

Increase weekly in increments of 18 mg per day, to a maximum dosage of 72 mg per day in adolescents

Inert components of tablet may be seen in stools

Increase to next patch size no more often than every week

Apply patch to hip and hold for 30 seconds; alternate hips every other day

Full effect is reached two hours after application; patch can be removed nine hours after application or sooner if desired; drug concentrations typically decrease after patch is removed, but drug absorption may continue for several hours

Patch cannot be cut

Used patches contain residual drug and should be disposed of properly

Increase weekly in increments of 10 to 20 mg per day

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Add 5- or 10-mg tablet in morning and/or at 4 p.m.

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Add 5- or 10-mg tablet in morning and/or at 4 p.m.

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Increase weekly in increments of 10 mg per day

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Add 5 or 10 mg of immediate-release formulation in morning and/or at 4 p.m.

Switching to long-acting formulation is generally equivalent to previous total daily dosage

After three days, increase dosage to 1.2 mg per kg per day, to a maximum dosage of 1.4 mg per kg per day; may be divided into two doses (morning and evening)

Full effect may not be reached for up to four weeks

Do not use concurrently with or within two weeks of taking monoamine oxidase inhibitors; concurrent use with cytochrome P450 CYP2D6 inhibitors may increase atomoxetine concentrations, requiring atomoxetine dose reduction

Discontinue use in patients who develop jaundice or evidence of liver injury

After three days, increase to 80 mg per day, to a maximum dosage of 100 mg per day; may be divided into two doses (morning and evening)

Increase by up to 1 mg per week, based on clinical response

Increased absorption when taken with high-fat meals

Metabolized by cytochrome CYP3A4 system; drug interactions possible

Not interchangeable with regular-release guanfacine

Safety and effectiveness of long-term use(longer than two years) have not been established