Clinical recommendation	Evidence rating	References
Flick sign, hypalgesia, square wrist sign, and a classic or probable pattern on hand symptom diagram are most discriminating for ruling in carpal tunnel syndrome.	C	7, 9, 10
Neutral and cock-up wrist splints produce short-term symptom relief in persons with carpal tunnel syndrome, with full-time use more effective than night-only use.	B	19, 20
Local and systemic corticosteroids yield significant resolution of symptoms in mild carpal tunnel syndrome for up to one month.	A	21