Degree of severitySymptoms and signsInitial PEF (or FEV1)Clinical course
MildDyspnea only with activity (assess tachypnea in young children)PEF ≥ 70 percent of predicted or personal bestUsually treated at home
Prompt relief with inhaled short-acting beta2 agonist
Possible short course of oral systemic corticosteroids
ModerateDyspnea interferes with or limits usual activityPEF 40 to 69 percent of predicted or personal bestUsually requires office or emergency department visit
Relief from frequent inhaled short-acting beta2 agonist
Oral systemic corticosteroids; some symptoms last for one to two days after treatment begins
SevereDyspnea at rest; interferes with conversationPEF < 40 percent of predicted or personal bestUsually requires emergency department visit and likely hospitalization
Partial relief from frequent inhaled short-acting beta2 agonist
Oral systemic corticosteroids; some symptoms last for more than three days after treatment begins
Adjunctive therapies are helpful
Subset: life threateningToo dyspneic to speak; perspirationPEF < 25 percent of predicted or personal bestRequires emergency department visit/hospitalization; possible intensive care unit
Minimal or no relief from frequent inhaled short-acting beta2 agonist
Intravenous corticosteroids
Adjunctive therapies are helpful