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Am Fam Physician. 2011;84(5):566-573

Guideline source: American Academy of Otolaryngology–Head and Neck Surgery

Evidence rating system used? Yes

Literature search described? Yes

Published source: Otolaryngology–Head and Neck Surgery, January 2011

Endorsed with qualifications by the AAFP, January 2013.

More than 530,000 tonsillectomies are performed in children and adolescents in the United States every year because of recurrent throat infections or sleep-disordered breathing. Although tonsillectomy is common and improves patients' quality of life, there are possible risks and practice variations in the care of patients undergoing tonsillectomy.

Recent guidelines from the American Academy of Otolaryngology–Head and Neck Surgery (AAO–HNS) aim to provide physicians with evidence-based guidance on identifying patients one to 18 years of age who would most benefit from the procedure. Table 1 summarizes the Paradise criteria for tonsillectomy used in this guideline, and Table 2 compares AAO–HNS, Italian, and Scottish guidelines.

Minimum frequency of sore throat episodesAt least seven episodes in the previous year, at least five episodes in each of the previous two years, or at least three episodes in each of the previous three years
Clinical featuresSore throat plus at least one of the following features qualifies as a counting episode:
Temperature of greater than 100.9°F (38.3°C)
Cervical adenopathy (tender lymph nodes or lymph node size greater than 2 cm)
Tonsillar exudate
Culture positive for group A β-hemolytic streptococcus
TreatmentAntibiotics administered in the conventional dosage for proved or suspected streptococcal episodes
DocumentationEach episode of throat infection and its qualifying features substantiated by contemporaneous notation in a medical record
If the episodes are not fully documented, subsequent observance by the physician of two episodes of throat infection with patterns of frequency and clinical features consistent with the initial history*
ParameterAAO–HNS guidelinesItalian guidelinesScottish guidelines
Target populationChildren and adolescents one to 18 years of ageChildren and adultsChildren four to 16 years of age and adults
ScopeTreatment of children who are candidates for tonsillectomyAppropriateness and safety of tonsillectomyManagement of sore throat and indications for tonsillectomy
MethodsBased on a priori protocol, systematic literature review, American Academy of Pediatrics scale of evidence qualitySystematic literature review, Italian National Program Guidelines scale of evidence qualityBased on a priori protocol, systematic literature review, Scottish Intercollegiate Guidelines Network scale of evidence quality
Recurrent infectionTonsillectomy is an option for children with recurrent throat infection that meets the Paradise criteria (Table 1) for frequency, severity, treatment, and documentation of illnessTonsillectomy is indicated in patients with at least one year of recurrent tonsillitis (five or more episodes per year) that is disabling and impairs normal activities, but only after an additional six months of watchful waiting to assess the pattern of symptoms using a clinical diaryTonsillectomy should be considered for recurrent, disabling sore throat due to acute tonsillitis when the episodes are well documented, are adequately treated, and meet the Paradise criteria (Table 1) for frequency of illness
Pain controlRecommendation to advocate for pain relief (e.g., provide information, prescribe) and educate caregivers about the importance of managing and reassessing painRecommendation for acetaminophen before and after surgeryRecommendation for adequate dose of acetaminophen for pain relief in children
Antibiotic useRecommendation against perioperative antibioticsRecommendation for short-term perioperative antibiotics*NA
Steroid useRecommendation for a single intraoperative dose of dexamethasoneRecommendation for a single intraoperative dose of dexamethasoneRecommendation for a single intraoperative dose of dexamethasone
Sleep-disordered breathingRecommendation to counsel caregivers about tonsillectomy as a means to improve health in children with sleep-disordered breathing and comorbid conditionsRecommendation for diagnostic testing in children with suspected sleep respiratory disordersNA
PolysomnographyRecommendation to counsel caregivers about tonsillectomy as a means to improve health in children with abnormal polysomnographyRecommendation for polysomnography when pulse oximetry results are not conclusive in agreement with Brouillette criteriaNA
Surgical techniqueNARecommendation for “cold” techniqueNA
HemorrhageRecommendation that the surgeon document primary and secondary hemorrhage after tonsillectomy at least annuallyNANA
Adjunctive therapyNANARecommendation against Echinacea purpurea for treatment of sore throat
Recommendation for acupuncture in patients at risk of postoperative nausea and vomiting who cannot take antiemetic drugs

Watchful Waiting for Recurrent Throat Infection

Watchful waiting is recommended for patients with recurrent throat infections if they have had fewer than seven episodes in the previous year, fewer than five episodes in each of the previous two years, or fewer than three episodes in each of the previous three years. At least 12 months of observation is recommended before considering tonsillectomy in patients without modifying factors. Observation beyond one year may be considered in patients meeting the Paradise criteria after the child's caregivers are counseled about the risks and benefits of the procedure in less severely affected children. However, prompt treatment is necessary in children with pharyngitis caused by group A β-hemolytic streptococcus.

Recurrent Throat Infection with Documentation

Documentation of recurrent throat infections should be used to help determine the need for tonsillectomy. Documentation for a throat infection includes the presence of a sore throat plus findings from a subjective physician assessment (e.g., fever, pharyngeal or tonsillar erythema, tonsil size, tonsillar exudate, cervical adenopathy, micro-biologic test results). Supportive documentation may include absences from school, spread of infection within the family, and family history of rheumatic heart disease or glomerulonephritis.

Tonsillectomy may be considered in patients with recurrent throat infections if they have had at least seven documented episodes of sore throat in the previous year, at least five documented episodes in each of the previous two years, or at least three documented episodes in each of the previous three years, plus a temperature of greater than 100.9°F (38.3°C), cervical adenopathy, tonsillar exudate, or a positive culture for group A β-hemolytic streptococcus. Evidence suggests that the most severely and frequently affected children have modest improvement with tonsillectomy; however, studies also suggest a notable improvement in quality of life. Caregivers should be advised of the harms and benefits of the procedure before a decision is made. If documentation is lacking, watchful waiting is appropriate while documentation of additional events is completed.

Tonsillectomy for Recurrent Infection with Modifying Factors

Children with recurrent throat infections who do not meet the initial criteria for tonsillectomy should be assessed for modifying factors that may make tonsillectomy favorable (e.g., those leading to risk of significant morbidity).

There are three categories of modifying risk factors. The first category includes exceptions to recognized criteria based on individual features of illness, such as multiple antibiotic allergies. The pattern of illness (e.g., throat episodes are very severe or poorly tolerated by the child) or drug allergies that make antimicrobial therapy difficult may influence the decision to perform a tonsillectomy. The second category includes specific clinical syndromes such as PFAPA (periodic fever, aphthous stomatitis, pharyngitis, and adenitis) or peritonsillar abscess. In these cases, tonsillectomy may be considered based on frequency and severity of illness and the patient's response to treatment. The last category, poorly validated clinical indications, may also influence the decision to perform tonsillectomy. The benefits of tonsillectomy for these conditions (e.g., halitosis, febrile seizures, malocclusion) must be weighed against the risks of surgery.

Tonsillectomy for Sleep-Disordered Breathing

Physicians should ask caregivers of children and adolescents with sleep-disordered breathing and tonsillar hypertrophy about comorbid conditions that could be improved with tonsillectomy. These conditions include growth retardation, poor school performance, enuresis, and behavioral problems.

Although polysomnography is often used to diagnose sleep-disordered breathing in children and adolescents, it is not always necessary. The diagnosis can be made using the history, physical examination, audiotaping or videotaping, pulse oximetry, or limited or full-night polysomnography. Tonsillar and adenoid hypertrophy are the most common causes of sleep-disordered breathing in children. Although studies support inquiring about comorbid conditions that may be improved with tonsillectomy to assist in decision making, there is a lack of randomized controlled trials supporting a recommendation for or against tonsillectomy in patients with these conditions.

Tonsillectomy and Polysomnography

Although polysomnography is not routinely needed in children with sleep-disordered breathing and tonsillar hypertrophy, some children and adolescents presenting for surgical consideration have already received poly-somnography testing. If these test results are abnormal, physicians should counsel caregivers about the benefits of tonsillectomy. Objectively documented sleep-disordered breathing and polysomnography results may warrant tonsillectomy, even without comorbid conditions. However, polysomnography results are broad, and there is no evidence-based cutoff that indicates the need for tonsillectomy.

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