Antiandrogenic properties

Alkylating agents

Bicalutamide (Casodex)

Cimetidine (Tagamet)

Cisplatin

Flutamide

Isoniazid

Ketoconazole

Marijuana

Methotrexate

Metronidazole (Flagyl)

Omeprazole (Prilosec)

Penicillamine (Cuprimine)

Ranitidine (Zantac)

Spironolactone (Aldactone)

Vinca alkaloids

Estrogenic properties

Anabolic steroids

Diazepam (Valium)

Digoxin

Estrogen agonists

Estrogens

Gonadotropin-releasing hormone agonists

Human chorionic gonadotropins

Phenytoin (Dilantin)

Phytoestrogens

Increases metabolism of androgens

Alcohol

Increases sex hormone–binding globulin concentration

Diazepam

Phenytoin

Induces hyperprolactinemia

Haloperidol

Metoclopramide (Reglan)

Phenothiazines

Unknown mechanism

Amiodarone

Amlodipine (Norvasc)

Amphetamines

Angiotensin-converting enzyme inhibitors

Antiretroviral agents

Atorvastatin (Lipitor)

Didanosine (Videx)

Diltiazem

Etomidate (Amidate)

Fenofibrate (Tricor)

Finasteride

Fluoxetine (Prozac)

Heroin

Methadone

Methyldopa

Minocycline (Minocin)

Minoxidil

Mirtazapine (Remeron)

Nifedipine (Procardia)

Nilutamide (Nilandron)

Paroxetine (Paxil)

Reserpine

Risperidone (Risperdal)

Rosuvastatin (Crestor)

Sulindac (Clinoril)

Theophylline

Tricyclic antidepressants

Venlafaxine (Effexor)

Verapamil