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Am Fam Physician. 2012;85(8):763-764

This is one in a series of pro/con editorials discussing controversial issues in family medicine.

Related editorials: Yes: Evidence Shows Benefit in Most Patients, and Yes: Spinal Manipulation Is a Useful Adjunct Therapy

See related Editor's note

Related article: Diagnosis and Treatment of Acute Low Back Pain

Author disclosure: No relevant financial affiliations to disclose.

Most adults experience low back pain at some point during their lives, making it one of the most common conditions encountered in primary care.1,2 The pain often improves greatly within one month, with more than 90 percent of patients no longer needing medical care within three months.3 The question is whether spinal manipulation, or any treatment, provides significant benefit given the benign natural history of low back pain.

Spinal manipulation involves the movement of joints along their anatomic range of motion in an attempt to improve and potentially prevent joint-related symptoms. The most consistent finding of several recent Cochrane reviews is that spinal manipulation may provide some statistically significant, but probably not clinically significant, differences in the short-term care of patients presenting with low back pain. Much of the evidence revealed low-quality studies, many of which had significant bias affecting the reliability and validity of the results. Of the higher-quality studies, one review of spinal manipulation for chronic low back pain found 26 randomized controlled trials (6,070 participants), but only nine of the studies were included because of concerns about bias.4 The review found no improvement in clinical end points compared with conventional therapies (e.g., exercise therapy, physiotherapy, standard medical care) other than a statistically significant, but likely clinically insignificant, improvement in pain relief (mean difference [MD] = -4.16; 95% confidence interval [CI], -6.97 to -1.36) and functional status (standardized MD = -0.22; 95% CI, -0.36 to -0.07).4

Another review that included 12 studies (2,887 participants) showed that combined chiropractic interventions addressing acute and subacute low back pain slightly improved short- and medium-term pain and disability (standardized MD = -0.25; 95% CI, -0.46 to -0.04, and MD = -0.89; 95% CI, -1.60 to -0.18, respectively).5 There was no difference associated with long-term outcomes (MD = -0.46; 95% CI, -1.18 to 0.26).5 A larger meta-analysis included 39 randomized controlled trials assessing the effect of spinal manipulation on short- and long-term pain and function in patients with acute and chronic low back pain.6 Spinal manipulation was no better statistically or clinically than general care, analgesics, physical therapy, exercises, or back school, and it was superior only to sham therapy or therapies identified as ineffective or harmful (10-mm difference [95% CI, 2 to 17 mm] on a 100-mm visual analog scale).6

Patients in pain are unhappy, and they want relief. The evidence shows that taking acetaminophen or a nonsteroidal anti-inflammatory drug and resting as needed is as effective as spinal manipulation. However, patients attribute pain resolution to active treatment. Although a course of spinal manipulation, or physical therapy, may keep the patient happy (and occupied) while his or her pain spontaneously resolves, the improvement in pain and function is not based on large, quality studies. Whether improved patient satisfaction with spinal manipulation versus watchful waiting is worth the cost of the therapy depends on who pays and how the paying party values satisfaction. As controlling costs becomes more important, incentives make watchful waiting with nonsteroidal anti-inflammatory drugs or acetaminophen the preferred approach.

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