San Francisco Syncope Rule3 ROSE risk score5 OESIL risk score6
Risk factors
  • Systolic blood pressure < 90 mm Hg

  • Shortness of breath

  • ECG: Nonsinus rhythm or new changes present

  • History of congestive heart failure

  • Hematocrit < 30 percent

  • Brain natriuretic peptide level ≥ 300 pg per mL (300 ng per L)

  • Bradycardia (≤ 50 beats per minute)

  • Rectal examination shows fecal occult blood

  • Anemia (hemoglobin level < 9.0 g per dL [90.0 g per L])

  • Chest pain associated with syncope

  • ECG with Q wave (not in lead III)

  • Oxygen saturation ≤ 94 percent on room air

  • Age > 65 years

  • History of cardiovascular disease

  • Syncope without a prodrome

  • Abnormal ECG findings

Risk groups*
No factors present: 0.3 percentNo factors present: 1.5 percent0 to 1 factor present (low risk): 0.6 percent
≥ 1 factors present: 15.2 percent≥ 1 factors present: 16.5 percent2 to 4 factors present (high risk): 31 percent
Accuracy of score
98 percent sensitive87 percent sensitive97 percent sensitive
56 percent specific66 percent specific73 percent specific
LR+ = 2.9LR+ = 2.5LR+ = 3.6
LR– = 0.03LR– = 0.2LR– = 0.11