Caregiver report of decreased tearing, sunken eyes, decreased urine output, or dry mucous membranes
Fever
	≥ 100.4°F (38°C) in infants younger than three months
	≥ 102.2°F (39°C) in children three to 36 months of age
Frequent and substantial episodes of diarrhea
History of premature birth, chronic medical conditions, or an accompanying illness
Mental status changes (e.g., apathy, lethargy, irritability)
Persistent vomiting
Poor response to oral rehydration therapy or inability of the caregiver to give adequate therapy
Visible blood in the stool
Young age (younger than six months) or low body weight
(less than 17 lb, 10 oz [8 kg])