| Younger than five years (preschool) | Oral amoxicillin (90 mg per kg per day in two doses*) | Oral azithromycin (Zithromax; 10 mg per kg on day 1, followed by 5 mg per kg per day once daily on days 2 through 5) | Oral oseltamivir (Tamiflu) |
| Alternative: oral amoxicillin/clavulanate (Augmentin; amoxicillin component, 90 mg per kg per day in two doses*) | Alternatives: oral clarithromycin (Biaxin; 15 mg per kg per day in two doses for seven to 14 days) or oral erythromycin (40 mg per kg per day in four doses) |
| Five years and older | Oral amoxicillin (90 mg per kg per day in two doses* to a maximum of 4 g per day†); for childrens with presumed bacterial CAP who do not have clinical, laboratory, or radiographic evidence that distinguishes bacterial CAP from atypical CAP, a macrolide can be added to a beta-lactam antibiotic for empiric therapy | Oral azithromycin (10 mg per kg on day 1, followed by 5 mg per kg per day once daily on days 2 through 5 to a maximum of 500 mg on day 1, followed by 250 mg on days 2 through 5) | Oral oseltamivir or zanamivir (Relenza; for children seven years and older) |
| Alternative: oral amoxicillin/clavulanate (amoxicillin component, 90 mg per kg per day in two doses* to a maximum of 4,000 mg per day [e.g., one 2,000-mg tablet twice daily*]) | Alternatives: oral clarithromycin (15 mg per kg per day in two doses to a maximum of 1 g per day); erythromycin, doxycycline for children older than seven years | Alternatives: intravenous oseltamivir and zanamivir are under clinical investigation in children; intravenous zanamivir available for compassionate use |
