Demographics

Advanced age

Overweight or obesity (particularly in postmenopausal women)

White race or Ashkenazi Jewish descent

Medical history

BRCA1 or BRCA2 mutation

First-degree relative with breast or ovarian cancer

History of atypical hyperplasia or lobular carcinoma in situ

One prior breast biopsy (regardless of results)

Personal history of breast or ovarian cancer

Medications and diet

Alcohol consumption (more than one drink per day)

Current or prior use of hormone therapy or oral contraceptives

Reproductive history

Menarche before 12 years of age

Menopause after 55 years of age

Nulliparity or age older than 35 years at first delivery

Other

High breast density on mammography

Prior thoracic radiation exposure