Agent	FDA pregnancy category	Adverse effects	Available formulations	Estimated cost generic (brand)*
Azelaic acid	B	Hypopigmentation, burning, stinging, tingling, pruritus	Cream (Azelex, 20%; approved for acne vulgaris)	NA ($210)
Azelaic acid	B	Hypopigmentation, burning, stinging, tingling, pruritus	Gel (Finacea, 15%; approved for rosacea)	NA ($210)
Benzoyl peroxide	C	Dry skin, local erythema	Bar, cream, gel, lotion, pad, wash (2.5% to 10%)	$5 over the counter
Benzoyl peroxide	C	Dry skin, local erythema	Bar, cream, gel, lotion, pad, wash (2.5% to 10%)	$8 to $36 prescription (NA)
Dapsone	C	Local oiliness, peeling, dryness, erythema	Gel (Aczone, 5%)	NA ($193)
Salicylic acid	C	Dryness, mild skin irritation	Cream, dressing, foam, gel, liquid, lotion, ointment, pad, paste, shampoo, soap, solution, stick (0.5% to 3%)	$5 over the counter