Component	Cost of generic (brand)	Dosage	Use if tympanic membrane perforation?	Comments
Acetic acid 2% (Vosol)	$39 for 15 mL* ($36 for 15 mL)*	Four to six times daily	No	May cause pain and irritation; may be less effective than other treatments if use is required beyond one week; often used as prophylactic agent
Ciprofloxacin 0.3%/dexamethasone 0.1% (Ciprodex)	Not available ($160 for 7.5 mL)*	Twice daily	Yes	Low risk of sensitization
Hydrocortisone 2%/acetic acid 1% (Vosol HC)	$220 for 10 mL† ($215 for 10 mL)*	Four to six times daily	No	May cause pain and irritation
Neomycin/polymyxin B/hydrocortisone, solution or suspension	$28 for 10-mL solution; $30 for 10-mL suspension† ($85 for 10-mL solution; $78 for 10-mL suspension)†	Three to four times daily	No	Ototoxic; higher risk of contact hypersensitivity; avoid in chronic/eczematous otitis externa4
Ofloxacin 0.3%	$60 for 5 mL; $93 for 10 mL† ($80 for 5 mL; $143 for10 mL)†	Once to twice daily	Yes	Low risk of sensitization