Potentiate the effects of warfarin (Coumadin)*

  • Antimicrobials

    Ciprofloxacin (Cipro)

    Clarithromycin (Biaxin)

    Erythromycin

    Isoniazid

    Metronidazole (Flagyl)

    Triazole antifungals

    Trimethoprim/sulfamethoxazole(Bactrim, Septra)

  • Cardiovascular

    Amiodarone

    Diltiazem

    Fibric acid derivatives

    Propafenone (Rythmol)

    Statins

  • Complementary and alternative medicineproducts

    Cranberry juice

    Danshen

    Fish oil

    Ginkgo biloba

    Red yeast rice

  • Miscellaneous

    Acetaminophen (dosages ≥ 1.3 g daily)

    Alcohol (acute ingestion)

    Cimetidine (Tagamet)

    Corticosteroids†

    Levothyroxine

    Omeprazole (Prilosec)

    Paroxetine (Paxil)

    Phenytoin (Dilantin)†

Decrease the effects of warfarin

  • Antimicrobials

    Griseofulvin

    Rifampin

  • Central nervous system drugs

    Barbiturates

    Carbamazepine (Tegretol)

    Chlordiazepoxide (Librium)

    Trazodone

  • Complementary and alternative medicineproducts

    American ginseng

    Coenzyme Q10

    St. John’s wort

  • Miscellaneous

    Cholestyramine (Questran)

    Corticosteroids†

    Mercaptopurine

    Phenytoin†