Medication	Dosage	Comments	Monitoring
Glucocorticoids
Prednisone	3 to 5 mg once daily	Use stress doses for illness, surgical procedures, and hospitalization	Symptoms of adrenal insufficiency; low to normal plasma adrenocorticotropic hormone levels indicate over-replacement
Hydrocortisone	15 to 25 mg divided into two or three doses per day	Use stress doses for illness, surgical procedures, and hospitalization
Dexamethasone	0.5 mg once daily	Use intramuscular dose for emergencies and when unable to tolerate oral intake
Mineralocorticoid
Fludrocortisone	0.05 to 0.2 mg once daily	Dosage may need to increase to 0.2 mg per day in the summer because of salt loss from perspiration	Blood pressure; serum sodium and potassium levels; plasma renin activity in the upper normal range
Androgen
Dehydroepiandrosterone (DHEA)	25 to 50 mg once daily	Available as an over-the-counter supplement; can improve mood and quality of life in women	Libido, mood, and sense of well-being