ProductDosing frequencyCommon adverse effectsCost for generic (brand)*
Topical antifungals
Ciclopirox 0.77% gel or cream (Ciclodan)Twice daily for up to four weeksBurning, contact dermatitis, pruritus$58 ($58) for 90-g tube of cream, $36 for 30-g tube of gel
Ketoconazole 2% cream, foam (Extina), or gel (Xolegel)Twice daily for eight weeks, then as neededBurning, irritation, photosensitivity$15 for 30-g tube of cream ($355 for 50-g can of Extina, $495 for 45-g tube of Xolegel)
Sertaconazole 2% cream (Ertaczo)Twice daily for up to four weeksContact dermatitis, tenderness, xerodermaNA ($423 for 60 g)
Topical calcineurin inhibitors
Pimecrolimus 1% cream (Elidel)Twice dailyBurning, headache, upper respiratory infectionNA ($204 for 30 g)
Tacrolimus 0.1% ointment (Protopic)Twice dailyBurning, influenza-like symptoms, pruritusNA ($234 for 30 g)
Topical corticosteroids
Betamethasone valerate 0.1% cream (Beta-Val) or lotionOnce or twice dailyHypopigmentation, skin atrophy, stinging, telangiectasia$13 ($7) for 15-g tube of cream; $25 ($13) for 60-mL bottle of lotion
Desonide 0.05% cream, foam (Verdeso), gel (Desonate), lotion (Lokara), or ointment (Desowen)Once or twice dailyBurning, hypopigmentation, skin atrophy, stinging, upper respiratory symptoms$15 for 15-g tube of cream; ($295 for 50-g can of Verdeso); ($419 for 60-g tube of Desonate); $73 ($73) for 59-mL bottle of lotion; $13 ($28) for 15-g tube of ointment
Fluocinolone 0.01% cream, oil (Derma Smoothe), or solution (Synalar)Once or twice dailyBurning, cough, dryness, fever, hypopigmentation, irritation, pruritus, rhinorrhea, skin atrophy$23 for 15-g tube of cream; $84 ($210) for 118-mL bottle of oil; $32 ($289) for 60-mL bottle of solution
Hydrocortisone 1% cream or ointmentOnce or twice dailyBurning, hypopigmentation, pruritus, skin atrophy$4 for 28-g tube of cream; $7 for 28-g tube of ointment