| Antihistamines and anticholinergics |
| Diphenhydramine (Benadryl) | 25 mg every 6 hours | $0.20 | Blurred vision, exacerbation of narrow-angle glaucoma (especially in older adults), sedation, urinary retention |
| Meclizine (Antivert) | 25 mg every 6 hours | $0.40 ($1.60) | |
| Scopolamine (Transderm Scop) | 1 patch every 3 days | ($18) | |
| Dopamine antagonists |
| Metoclopramide (Reglan) | 10 mg every 4 hours | $0.20 ($2.30) | Extrapyramidal effects, hypotension, QT prolongation, sedation |
| Prochlorperazine | 5 to 10 mg every 6 hours | $0.35 | |
| Promethazine | 12.5 to 25 mg every 6 hours | $0.50 | |
| Serotonin antagonist |
| Ondansetron (Zofran) | 2 mg orally or intravenously | Intravenous: $4 ($26) | Hypersensitivity reactions (rare), QRS widening, QT prolongation |
| | Oral: $1.40 ($22) | |
| Other agents |
| Methylprednisolone (Depo-Medrol) | 40 mg intravenously | $9 ($11) | Corticosteroids: exacerbation of hypertension, fluid retention, hyperglycemia, psychiatric disturbance |
| Dexamethasone | 4 to 8 mg intravenously | $4 | |
| Ginger | 250 mg every 6 hours | $0.10 | |
| Doxylamine/pyridoxine (Diclegis) | 2 to 4 tablets per day | $6 | |
| Pyridoxine | 10 to 25 mg every 8 hours | $0.05 | |
