Medication		Estimated cost*
First line
Selective serotonin reuptake inhibitors
	Escitalopram (Lexapro)	$25 ($190)
	Fluoxetine (Prozac)	$5 ($250)
	Fluvoxamine for PD	$15 (NA)
	Paroxetine (Paxil)	$5 ($150)
	Sertraline (Zoloft)	$10 ($200)
Serotonin-norepinephrine reuptake inhibitors
	Duloxetine (Cymbalta) for GAD	$50 ($210)
	Venlafaxine, extended release (Effexor XR)	$15 ($230)
Azapirone
	Buspirone (Buspar) for GAD	$5 ($87)
Second line
Tricyclic antidepressants
	Amitriptyline†	$5 (NA)
	Imipramine (Tofranil)‡	$10 ($265)
	Nortriptyline (Pamelor)†	$10 ($725)
Antiepileptics
	Pregabalin (Lyrica)† for GAD	NA ($145)
Antipsychotics
	Quetiapine (Seroquel)† for GAD	$15 ($130)
Hydroxyzine (Vistaril)		$12 ($200)
Third line
Monoamine oxidase inhibitors§
	Isocarboxazid (Marplan)†	NA ($130)
	Phenelzine (Nardil)†	$20 ($50)
	Tranylcypromine (Parnate)†	$50 ($185)
Augmentation
Benzodiazepines||
	Alprazolam (Xanax) ¶	$10 ($70)
	Clonazepam (Klonopin)**	$10 ($70)
	Diazepam (Valium) for GAD	$10 ($90)
	Lorazepam (Ativan)‡	$10 ($300)