Clinical recommendation	Evidence rating	References
Physical activity is a cost-effective treatment for GAD and PD.	B	16, 17
Selective serotonin reuptake inhibitors are considered first-line therapy for GAD and PD.	B	19, 20, 22
To avoid relapse, medication should be continued for 12 months after symptoms improve before tapering.	C	11
When used in combination with antidepressants, benzodiazepines may speed recovery from anxiety-related symptoms but do not improve longer-term outcomes. Because benzodiazepines are associated with tolerance, they should be used only short term during crises.	B	11, 28–30
Psychotherapy can be as effective as medication for GAD and PD. Cognitive behavior therapy has the best level of evidence.	A	11, 37
Successful treatment requires tailoring options to individuals and may often include a combination of modalities.	C	11, 37, 42