What are the effects of oral treatments for fungal toenail infections in adults?

  • Beneficial

  • Itraconazole (more effective than placebo, but probably less effective than terbinafine)

  • Terbinafine

  • Likely to be beneficial

  • Fluconazole (although benefits are modest, even after long-term treatment)

What are the effects of topical treatments for fungal toenail infections in adults?

  • Likely to be beneficial

  • Ciclopirox (although benefits are modest, even after long-term treatment)

  • Unknown effectiveness

  • Amorolfine

  • Butenafine

  • Fluconazole

  • Ketoconazole

  • Terbinafine

  • Tioconazole