Patient characteristics	Treatment options
Asymptomatic women	Clinical surveillance4
Infertile women with distorted uterine cavity (i.e., submucosal fibroids) who desire future fertility	Myomectomy16
Symptomatic women who desire future fertility	Medical treatment or myomectomy 34,38,41
Symptomatic women who do not desire future fertility but wish to preserve the uterus	Medical treatment, myomectomy, uterine artery embolization, magnetic resonance–guided focused ultrasound surgery 34,38,40–42
Symptomatic women who want definitive treatment and do not desire future fertility	Hysterectomy by least invasive approach possible43,44