| Rapid acting |
| Aspart (Novolog) | 28 days | 28 days |
| Glulisine (Apidra) | 28 days | 28 days |
| Lispro (Humalog) | 28 days | 28 days |
|
| Short acting |
| Regular (Humulin R) U-100 | 31 to 42 days, depending on the brand | — |
|
| Intermediate acting |
| Isophane (NPH; Humulin N) | 31 to 42 days, depending on the brand | 14 days |
|
| Long acting |
| Detemir (Levemir) | 6 weeks | 6 weeks |
| Glargine (Lantus, Basaglar) | 4 weeks | 4 weeks |
| Glargine (Toujeo Solostar) | — | 6 weeks |
|
| Ultra–long acting |
| Regular U-500 | 40 days | 4 weeks |
| Degludec (Tresiba Flextouch) | — | 8 weeks |
|
| Premixed |
| 70% isophane/30% regular (Humulin 70/30) | 31 days | 10 days |
| 70% isophane/30% regular (Novolin 70/30) | 42 days | — |
| 70% aspart protamine/30% aspart (Novolog Mix 70/30) | 28 days | 14 days |
| 50% lispro protamine/50% lispro (Humalog Mix 50/50) | 28 days | 10 days |
| 75% lispro protamine/25% lispro (Humalog Mix 75/25) | 28 days | 10 days |
| 70% degludec/30% aspart (Ryzodeg) | — | 28 days |
