Diagnosis	Primary management option	Alternate options
Papulosquamous lesions
Psoriasis	Topical corticosteroids	Vitamin D3 analogues, tacrolimus (Protopic), pimecrolimus (Elidel)
Inflammatory lesions
Lichen sclerosus	Topical corticosteroids	Circumcision if isolated to the prepuce
Lichen nitidus	Observation	Topical corticosteroids, tacrolimus, pimecrolimus
Lichen planus	Topical corticosteroids	Circumcision if isolated to the prepuce
Vascular lesions
Angiokeratomas	Observation	Surgery, cryoablation, electrocautery, laser ablation
Neoplastic lesions
Carcinoma in situ	Circumcision for isolated prepuce lesions	Mohs micrographic surgery, topical imiquimod (Aldara)
Invasive squamous cell carcinoma	Circumcision for isolated prepuce lesions; Mohs micrographic surgery for non-isolated lesions	Partial or radical penectomy, radiation, brachytherapy