StageDescriptionStageDescription

Primary tumor (pathological)Regional LN (continued)
pTXPrimary tumor cannot be assessedPathologic
pT0No evidence of primary tumorpNXRegional LN cannot be assessed
pTisGerm cell neoplasia in situpN0No regional LN metastasis on biopsy
pT1Tumor limited to the testis (including rete testis invasion) without LVIpN1Metastasis with LN mass 2 cm or smaller in greatest dimension; five or fewer nodes positive, none larger than 2 cm in greatest dimension
pT1aTumor smaller than 3 cm in size*pN2Metastasis with LN mass larger than 2 cm but not larger than 5 cm in greatest dimension; more than five nodes positive, none larger than 5 cm in greatest dimension; or evidence of extranodal extension of tumor
pT1bTumor 3 cm or larger in size*pN3Metastasis with LN mass larger than 5 cm in greatest dimension
pT2Tumor limited to the testis (including rete testis invasion) with LVI; or tumor invading hilar soft tissue or epididymis, or penetrating visceral mesothelial layer covering the external surface of the tunica albuginea with or without LVIDistant metastasis
pT3Tumor invades the spermatic cord with or without LVIM0No distant metastasis
pT4Tumor invades the scrotum with or without LVIM1Distant metastasis present
Regional LNM1aNonretroperitoneal nodal or pulmonary metastasis
ClinicalM1bNonpulmonary visceral metastasis
cNXRegional LN cannot be assessed
cN0No regional LN metastasis on imaging
cN1Metastasis with LN mass 2 cm or smaller in greatest dimension; or multiple LNs, none larger than 2 cm in greatest dimension
cN2Metastasis with LN mass larger than 2 cm but not larger than 5 cm in greatest dimension; or multiple LNs, any one mass larger than 2 cm but not larger than 5 cm in greatest dimension
cN3Metastasis with LN mass larger than 5 cm in greatest dimension
StageDescription

Serum biomarkers
Lactate dehydrogenaseHuman chorionic gonadotropinAlpha fetoprotein
SXBiomarkers not available or not measured
S0NormalNormalNormal
S1< 1.5 times normal< 5,000 mIU per mL (5,000 IU per L)< 1,000 ng per mL (1,000 mcg per L)
S21.5 to 10 times normal5,000 to 50,000 mIU per mL (5,000 to 50,000 IU per L)1,000 to 10,000 ng per mL (1,000 to 10,000 mcg per L)
S3> 10 times normal> 50,000 mIU per mL> 10,000 ng per mL