Intervention	Indications	Comments
CABG61,62	Patients with refractory symptoms and left main coronary artery stenosis (≥ 50%), three-vessel disease with or without LAD artery disease, or abnormal left ventricular function (ejection fraction < 35% to 50%)	First-line treatment in patients with left main coronary artery stenosis or three-vessel disease Use caution in patients with one-vessel disease not involving LAD artery or no physiologic criteria for revascularization
Percutaneous coronary intervention59–61	Consider in patients with refractory angina despite optimal medical therapy Alternative to CABG in patients with low risk of complications and high likelihood of success	Use caution in patients with unfavorable anatomy or high risk of postoperative complications