Age 40 years or older for patients with type 1 diabetes mellitus

Age 50 years or older for patients with type 2 diabetes

Computed tomography shows osseous fracture(s), particularly about the midfoot

Diagnosis of type 1 or 2 diabetes for 10 years or more

Increased tracer uptake in all three phases of a bone scan and negative white blood cell–tagged scan

Magnetic resonance imaging shows periarticular bone marrow edema, which enhances on postcontrast images

Minimal or no foot pain

No systemic or laboratory findings concerning for infection

No trauma or only minor trauma reported

Obesity

Peripheral neuropathy of any etiology

Radiography reveals increased soft tissue volume, subtle subluxations, or ligamentous avulsion fractures, particularly about the midfoot

Treatment for recurrent cellulitis

Unilateral edematous, erythematous, warm limb with no open wounds

Venous duplex ultrasonography is negative for deep venous thrombosis