Drug	Amount of elemental iron	Dosing	Comments
Ferric carboxymaltose (Injectafer)	750 mg per 15 mL of solution	Patients ≥ 50 kg (110 lb):750 mg in two doses seven days apart	Monitor for hypersensitivity and hypertension (3.8%) vs. hypotension (1%)
		Patients < 50 kg: 15 mg per kg in two doses seven days apart
Ferric gluconate (Ferrlecit)	62.5 mg per 5 mL of solution	10 mL diluted in 100 mL of saline over multiple treatments	Give 2-mL test dose diluted in 50 mL of saline infused over one hour before first infusion
Ferumoxytol (Feraheme)	510 mg per 17 mL of solution	17-mL injection initially, then a second injection three to eight days later	U.S. Food and Drug Administration boxed warning regarding serious risk of allergic reaction; monitor for hypersensitivity and hypotension
Iron dextran (Infed)	50 mg per 1 mL of solution	Multiple doses based on weight and hemoglobin level	Give 0.5-mL test dose one hour before first infusion
Iron sucrose (Venofer)	20 mg per 1 mL of solution	5 mL over multiple treatments one to three times per week	—