Evidence sourceFindings
Systematic review and meta-analysis38 MBIs were superior to no treatment, minimal treatment, nonspecific active controls, and specific active controls
Meta-analysis of 39 studies of mindfulness-based therapies for anxiety and depression39 Mindfulness-based therapies were moderately effective for improving anxiety and mood symptoms in pre-post analyses
Systematic review of mindfulness-based therapies40 Mindfulness-based therapies showed large and clinically significant effects on anxiety and depression, which were maintained at follow-up
Meta-analysis of RCTs of MBIs for current episodes of anxiety or depressive disorder 41 MBIs significantly improved primary symptom severity in people with depression (outcomes may be similar to those achieved with group cognitive behavior therapy); results did not support MBIs for anxiety disorder
Review of mindfulness-based meditation as self-help for anxiety and depression42 Mindfulness-based meditation may be viable approach to treatment of anxiety and depression, but more rigorous studies are needed
RCT of MBCT for relapse or recurrence of depression over two years of follow-up43 MBCT seemed to work well in combination with antidepressant therapy; combined treatment (MBCT plus medication) may be an effective option for many people with extensive histories of recurrent depression
Meta-analysis of 18 studies of stand-alone MBIs for symptoms of anxiety and depression44 MBIs had small to medium effects on anxiety and depression compared with controls
RCT of MBCT vs. control for depression45 MBCT reduced symptoms of depression in people with traumatic brain injury, as measured by the Beck Depression Inventory II; reduction was maintained at three-month follow-up
RCT of MBSR vs. person-centered group therapy in military veterans with posttraumatic stress disorder47 MBSR group had greater improvement in self-reported severity of posttraumatic stress disorder symptoms during treatment and at two-month follow-up
RCT of MBSR vs. aerobic exercise for social anxiety disorder48 MBSR and aerobic exercise reduced social anxiety and depression, and increased subjective well-being immediately and at three months postintervention