Outcomes	Assumed risk	Corresponding risk (95% CI)	ARR (95% CI)	NNT (95% CI)
Angiotensin-converting enzyme inhibitors
Cardiovascular mortality	86 per 1,000	81 per 1,000 (53 to 123)	NA	NA
Heart failure hospitalization	13 per 1,000	11 per 1,000 (8 to 15)	NA	NA
Angiotensin receptor blockers
All-cause mortality	72 per 1,000	73 per 1,000 (66 to 80)	NA	NA
Cardiovascular mortality	131 per 1,000	133 per 1,000 (118 to 149)	NA	NA
Heart failure hospitalization	171 per 1,000	157 per 1,000 (142 to 174)	NA	NA
Beta blockers
All-cause mortality	243 per 1,000	199 per 1,000 (163 to 243)	NA	NA
Cardiovascular mortality	173 per 1,000	135 per 1,000 (107 to 171)	0.038 (0.002 to 0.066)	26 (15 to 500)
Heart failure hospitalization	117 per 1,000	86 per 1,000 (55 to 133)	NA	NA
Mineralocorticoid receptor antagonists
All-cause mortality	133 per 1,000	121 per 1,000 (104 to 141)	NA	NA
Cardiovascular mortality	88 per 1,000	79 per 1,000 (65 to 97)	NA	NA
Heart failure hospitalization	136 per 1,000	112 per 1,000 (94 to 134)	0.024 (0.002 to 0.042)	42 (23 to 500)