| Smoking cessation and weight loss should be encouraged to decrease disease severity and improve response to treatment.3,4,11,12 |
B |
Consistent results from lower-quality cohort studies |
| Topical clindamycin and oral tetracycline antibiotics are effective for patients with mild to moderate hidradenitis suppurativa.15,19,27 |
B |
Evidence from limited-quality RCTs |
| Adalimumab (Humira) is effective for patients with moderate to severe hidradenitis suppurativa.24,25,27 |
A |
Consistent evidence from high-quality RCTs |
| Wide excision is the definitive treatment for severe hidradenitis with extensive involvement and scarring.34,35 |
B |
Systematic review and meta-analysis of lower-quality clinical trials |
