Population	Eighth Joint National Committee, 2014	European Society of Cardiology, 2018	American College of Cardiology/American Heart Association, 2017
General nonblack population	ACEI/ARB or CCB or thiazide diuretic	ACEI/ARB plus CCB or thiazide diuretic	ACEI/ARB or CCB or thiazide diuretic
General black population	ACEI/ARB* or CCB or thiazide diuretic	ACEI/ARB* or CCB or thiazide diuretic	No specific recommendation
Adults with diabetes mellitus	ACEI/ARB or CCB or thiazide diuretic	ACEI/ARB plus CCB or thiazide diuretic	ACEI/ARB or CCB or thiazide diuretic
Adults with chronic kidney disease and proteinuria (regardless of race)	ACEI/ARB plus CCB or thiazide diuretic	ACEI/ARB plus CCB or diuretic (thiazide or loop)†	ACEI/ARB plus CCB or thiazide diuretic
Heart failure with reduced ejection fraction	No specific recommendation	ACEI/ARB/ARNI plus beta blocker‡ plus diuretic (thiazide or loop)†	ACEI/ARB or beta blocker‡ or miner-alocorticoid receptor antagonist or thiazide diuretic