Headache type	Acute treatments	Chemoprophylaxis*
Migraine	Acetaminophen, 1,000 mg	Amitriptyline, 10 to 150 mg at bedtime
	Acetaminophen/aspirin/caffeine, 500 mg/500 mg/130 mg	Atenolol, 50 to 200 mg daily
	Almotriptan, 12.5 mg	Candesartan (Atacand), 16 mg daily
	Aspirin, 900 to 1,000 mg	Divalproex (Depakote), 250 to 750 mg twice daily
	Eletriptan (Relpax), 20 to 80 mg
	Frovatriptan (Frova), 2.5 mg	Metoprolol, 50 to 100 mg twice daily
	Ibuprofen, 200 to 400 mg
	Naproxen, 500 to 825 mg	Nadolol (Corgard), 80 to 160 mg daily
	Naratriptan (Amerge), 1 to 2.5 mg	Nortriptyline (Pamelor), 10 to
	Rizatriptan (Maxalt), 5 to 10 mg	100 mg at bedtime
	Sumatriptan (Imitrex), 25 to 100 mg orally, 10 to 20 mg intranasally, or 4 to 6 mg subcutaneously	Propranolol, 40 to 160 mg twice daily
	Sumatriptan/naproxen (Treximet), 85 mg/500 mg	Topiramate (Topamax), 25 to 200 mg daily
	Zolmitriptan (Zomig), 2.5 mg orally or 2.5 to 5 mg intranasally	Valproate (Depacon), 400 to 1,500 mg daily
Tension	Acetaminophen, 1,000 mg	Amitriptyline, 10 to 75 mg at bedtime
	Aspirin, 500 to 1,000 mg	Nortriptyline, 10 to 100 mg at bedtime
	Diclofenac, 12.5 to 25 mg
	Ibuprofen, 200 to 800 mg
	Ketoprofen, 25 mg
	Naproxen, 375 to 550 mg
Cluster	Oxygen 100%, 7 to 12 L per minute for 15 minutes	Civamide (not available in the United States), 100 mcg intranasally
	Sumatriptan, 6 mg subcutaneously	Lithium, 900 to 1,200 mg daily
	Zolmitriptan, 5 mg intranasally
		Verapamil, 240 to 960 mg daily
Rare primary headaches	May respond to indomethacin	—