Osmotic Citrates, phosphates, sulfates Magnesium-containing antacids and laxatives Sugar alcohols (e.g., mannitol, sorbitol, xylitol) Secretory Antiarrhythmics (e.g., quinine) Antibiotics (e.g., amoxicillin/clavulanate [Augmentin]) Antineoplastics Biguanides Calcitonin Cardiac glycosides (e.g., digitalis) Colchicine Nonsteroidal anti-inflammatory drugs (may contribute to microscopic colitis) Prostaglandins (e.g., misoprostol [Cytotec])

Motility Macrolides (e.g., erythromycin) Metoclopramide (Reglan) Stimulant laxatives (e.g., bisacodyl [Dulcolax], senna [Senokot]) Malabsorption Acarbose (Precose; carbohydrate malabsorption) Aminoglycosides Orlistat (Xenical; fat malabsorption) Thyroid supplements Pseudomembranous colitis (Clostridioides difficile) Antibiotics (e.g., clindamycin, fluoroquinolones, cephalosporins, penicillin) Antineoplastics Immunosuppressants Proton pump inhibitors (can also cause diarrhea through other mechanisms)