| A discriminatory β-hCG level as high as 3,500 mIU per mL (3,500 IU per L) should be used when a woman wishes to avoid unnecessary intervention in a potentially viable intrauterine pregnancy.18,19 |
C |
Expert opinion and consensus guideline in the absence of clinical trials |
| Uterine aspiration should be considered to evaluate for intrauterine chorionic villi in patients with a pregnancy of unknown location. Visualization of chorionic villi differentiates intrauterine pregnancy loss from ectopic pregnancy, avoiding unnecessary administration of methotrexate.5 |
C |
Expert opinion and consensus guideline in the absence of clinical trials |
| A single-dose methotrexate protocol is recommended for medical management of patients with ectopic pregnancy and low initial β-hCG levels.5 |
C |
Expert opinion and consensus guideline in the absence of clinical trials |
| Urgent surgical referral is indicated when ultrasonography demonstrates an embryo and fetal cardiac activity outside of the uterus.5,25 |
C |
Expert opinion and consensus guideline in the absence of clinical trials |
