Outcomes	Risk with control	Risk with corticosteroids (95% CI)	NNT (95% CI)*	Participants (studies)	Quality of evidence (GRADE)
30-day mortality in adults	82 per 1,000	53 per 1,000 (38 to 74)	34 (24 to 125)	1,863 (11 RCTs)	Moderate
30-day mortality in adults with severe CAP (PSI > 4)7	131 per 1,000	76 per 1,000 (52 to 110)	18 (13 to 48)	995 (9 RCTs)	Moderate
30-day mortality in adults with nonsevere CAP	29 per 1,000	28 per 1,000 (13 to 58)	—	868 (4 RCTs)	Moderate
Early clinical failure in adults	373 per 1,000	149 per 1,000 (86 to 261)	5 (4 to 9)	1,324 (6 RCTs)	Moderate
Early clinical failure in adults with severe CAP (PSI > 4)7	422 per 1,000	135 per 1,000 (63 to 296)	4 (3 to 8)	419 (5 RCTs)	High
Early clinical failure in adults with nonsevere CAP	352 per 1,000	240 per 1,000 (197 to 292)	9 (7 to 17)	905 (2 RCTs)	High
Early clinical failure in children	659 per 1,000	270 per 1,000 (158 to 461)	3 (2 to 5)	88 (2 RCTs)	High